Publications
(Imported from Google Scholar)
| Self-localized ultrafast pencil beam for volumetric multiphoton imaging
H Cao, S Spitz, LY Yu, K Liu, Z Zhang, F Presutti, FM Pramotton, …
Nature Methods, 1-13
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1 | 2026 |
| Tunable supercontinuum in multimode fiber via bending-induced dispersion modification
LY Yu, H Cao, K Liu, C Li, B Weissbourd, S Kulkarni, S You
arXiv preprint arXiv:2603.12593
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2026 | |
| MAD: Microenvironment-Aware Distillation–A Pretraining Strategy for Virtual Spatial Omics from Microscopy
J Han, K Liu, Y Kim, S Sinha, S You
arXiv preprint arXiv:2603.13401
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2026 | |
| Volumetric imaging of live biological systems via an ultrafast self-localized pencil beam
H Cao, LY Yu, K Liu, S You
High-Throughput Biophotonics: Imaging, Spectroscopy, and Beyond XI, PC1386205
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2026 | |
| Single shot, 3-photon fluorescence lifetime imaging for deep and fast metabolic microscopy
J Tomkiewicz, F Presutti, S You
Label-free Biomedical Imaging and Sensing (LBIS) 2026, PC1386306
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2026 | |
| Roadmap on deep learning for microscopy
G Volpe, C Wählby, L Tian, M Hecht, A Yakimovich, K Monakhova, …
Journal of Physics: Photonics 8 (1), 012501
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34 | 2026 |
| A microphysiological model of human MASLD reveals paradoxical response to resmetirom
DJ Hellen, J Ungerleider, E Tevonian, P Sphabmixay, P Roy, N Meimetis, …
Communications Biology
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2026 | |
| Beyond genetics: Lyme disease’s unexpected role in connective tissue health-findings from a murine model for borrelia burgdorferi infection and the human clinical study MAESTRO …
G Loeser, Q Feng, K Liu, B Pollack, G Pisani, A Kitjasateanphun, S You, …
The Journal of Immunology 214 (Supplement_1), vkaf283. 1711
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2025 | |
| Lyme disease increases risk for uterine conditions and gynepathologies 2029
PH Colburn, G Blacker, SD Galloway, Q Feng, P Padmanabham, B Lee, …
The Journal of Immunology 214 (Supplement_1), vkaf283. 003
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2025 | |
| Simultaneous Label-free Imaging of Nucleolar Dynamics and Subcellular Metabolic Shifts Across Tissue Contexts
K Liu, EL Kan, H Cao, J Han, G Nola, LG Griffith, E Calo, S You
bioRxiv, 2025.10. 07.681013
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2025 | |
| Ring deconvolution microscopy: exploiting symmetry for efficient spatially varying aberration correction
A Kohli, AN Angelopoulos, D McAllister, E Whang, S You, K Yanny, …
Nature methods 22 (6), 1311-1320
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16 | 2025 |
| Deep and Isotropic Structural and Metabolic Imaging for Nucleolar Dynamics in Living Biosystems
K Liu, EL Kan, H Cao, J Han, LG Griffith, E Calo, S You
Bio-Optics: Design and Application, DTu3A. 3
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2025 | |
| Adaptive Multimode Fiber Source for Label-Free Nonlinear Microscopy
LY Yu, H Cao, K Liu, T Qiu, S You
Novel Techniques in Microscopy, NM3C. 4
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2025 | |
| Multiplexed Nonlinear Microscopy via High-Peak-Power Tunable Broadband Fiber Source
LY Yu, H Cao, K Liu, S You
Bio-Optics: Design and Application, DM5A. 5
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2025 | |
| Adaptive multimode fiber source for deep nonlinear microscopy
H Cao, LY Yu, K Liu, S You
Adaptive Optics and Wavefront Control for Biological Systems XI, PC1332809
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2025 | |
| High-energy, self-organized beam delivered by multimode fiber for volumetric multiphoton imaging
H Cao, K Liu, K Shashaty, S You
Multiphoton Microscopy in the Biomedical Sciences XXV, PC133240Z
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2025 | |
| Learned, uncertainty-driven adaptive acquisition for photon-efficient scanning microscopy
CT Ye, J Han, K Liu, A Angelopoulos, L Griffith, K Monakhova, S You
Optics Express 33 (6), 12269-12287
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9 | 2025 |
| Lyme disease increases risk for multiple gynecological conditions
HC PS, G Blacker, S Galloway, Q Feng, PS Padmanabham, G Pisani, …
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2025 | |
| Lyme disease increases risk for multiple gynecological conditions
PS Hansen Colburn, G Blacker, S Galloway, Q Feng, PS Padmanabham, …
medRxiv, 2025.03. 03.25323258
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2025 | |
| Consensus guidelines for cellular label-free optical metabolic imaging: ensuring accuracy and reproducibility in metabolic profiling
I Georgakoudi, MC Skala, KP Quinn, C Stringari, JE Sorrells, AA Heikal, …
Journal of biomedical optics 30 (S2), S23901-S23901
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9 | 2025 |
| System-and sample-agnostic isotropic three-dimensional microscopy by weakly physics-informed, domain-shift-resistant axial deblurring
J Han, K Liu, KB Isaacson, K Monakhova, LG Griffith, S You
Nature Communications 16 (1), 745
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11 | 2025 |
| Deep and dynamic metabolic and structural imaging in living tissues
K Liu, H Cao, K Shashaty, LY Yu, S Spitz, FM Pramotton, Z Wan, EL Kan, …
Science Advances 10 (50), eadp2438
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14 | 2024 |
| Spatiotemporal control of light propogating through a fiber
S You, T Qiu, H Cao, K LIU
US Patent App. 18/678,655
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2024 | |
| Clipping-assisted dual-fluorophore sensing
SA Boppart, H Tu, S You
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2024 | |
| Clipping-assisted dual-fluorophore sensing
SA Boppart, H Tu, S You
US Patent 12,092,576
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2 | 2024 |
| High-Fidelity and High-Speed Wavefront Shaping by Leveraging Complex Media
LY Yu, S You
Science Advances 10 (27)
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9* | 2024 |
| EventLFM: event camera integrated Fourier light field microscopy for ultrafast 3D imaging
R Guo, Q Yang, AS Chang, G Hu, J Greene, CV Gabel, S You, L Tian
Light: Science & Applications 13 (1), 144
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57 | 2024 |
| System-and sample-agnostic isotropic 3D microscopy by weakly physics-informed, domain-shift-resistant axial deblurring
J Han, K Liu, KB Isaacson, K Monakhova, LG Griffith, S You
arXiv preprint arXiv:2406.06337
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2 | 2024 |
| Biological discovery driven by AI-assisted label-free microscopy
S You
Computational Optical Imaging and Artificial Intelligence in Biomedical …
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2024 | |
| Leveraging uncertainty quantification in adaptive multiphoton microscopy acquisition
CT Ye, J Han, K Liu, A Angelopoulos, L Griffith, K Monakhova, S You
Computational Optical Imaging and Artificial Intelligence in Biomedical …
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2024 | |
| Tunable broadband fiber source for multiplexed nonlinear microscopy
L Yu, H Cao, K Liu, T Qiu, S You
Photonics and Optoelectronics, 150
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2024 | |
| High-speed simultaneous label-free autofluorescence-multiharmonic (hSLAM) microscopy for multicellular dynamics
K Liu, T Qiu, H Cao, LG Griffith, F Wang, S You
Label-free Biomedical Imaging and Sensing (LBIS) 2024, PC1285406
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2024 | |
| Spectral-temporal-spatial customization via modulating multimodal nonlinear pulse propagation
T Qiu, H Cao, K Liu, LY Yu, M Levy, E Lendaro, F Wang, S You
Nature Communications 15 (1), 2031
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38* | 2024 |
| Learned, uncertainty-driven adaptive acquisition for photon-efficient multiphoton microscopy
CT Ye, J Han, K Liu, A Angelopoulos, L Griffith, K Monakhova, S You
arXiv preprint arXiv:2310.16102
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8 | 2023 |
| Adaptive Fiber Source for High-Speed Label-Free Multimodal Multiphoton Microscopy
K Liu, T Qiu, H Cao, S You
Imaging Systems and Applications, ITu5E. 4
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2023 | |
| An Energetic, Tunable, Ultra-Broadband Fiber Source for Imaging and Spectroscopy
T Qiu, H Cao, K Liu, S You
Optica | Novel Techniques in Microscopy
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2023 | |
| Ring deconvolution microscopy: An exact solution for spatially-varying aberration correction
A Kohli, AN Angelopoulos, D McAllister, E Whang, S You, K Yanny, …
arXiv preprint arXiv:2206.08928
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7 | 2022 |
| Label-free optical redox ratio from urinary extracellular vesicles as a screening biomarker for bladder cancer
J Park, RL Kamerer, M Marjanovic, JE Sorrells, S You, R Barkalifa, …
American Journal of Cancer Research 12 (5), 2068
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12 | 2022 |
| Linear revolution-invariance: Modeling and deblurring spatially-varying imaging systems
A Kohli, A Angelopoulos, S You, K Yanny, L Waller
arXiv preprint
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3 | 2022 |
| Wound-like tumor periphery in human breast cancer predicts a convergent drug nonresponse
L Li, X Liao, F Fu, G Xi, D Kang, J He, W Guo, L Qiu, Z Han, X Wang, …
bioRxiv, 2021.11. 02.467008
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1 | 2021 |
| Shift-variant deblurring for rotationally symmetric systems
A Kohli, A Angelopoulos, S You, L Waller
Computational Optical Sensing and Imaging, CTh5A. 4
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2 | 2021 |
| The cholesterol metabolite 27HC increases secretion of extracellular vesicles which promote breast cancer progression
AE Baek, N Krawczynska, A Das Gupta, SV Dvoretskiy, S You, J Park, …
Endocrinology 162 (7), bqab095
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46 | 2021 |
| Label-free deep profiling of the tumor microenvironment
S You, EJ Chaney, H Tu, Y Sun, S Sinha, SA Boppart
Cancer research 81 (9), 2534-2544
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41 | 2021 |
| label-free multimodal nonlinear imaging of the treatment response in pancreatic tumor patient-derived xenografts in mice
J Park, E Chaney, S You, A Abdelrahman, J Leiting, J Yonkus, P Groves, …
Label-free Biomedical Imaging and Sensing (LBIS) 2021 11655, 116550J
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2021 | |
| Real-time three-dimensional histology-like imaging by label-free nonlinear optical microscopy
Y Sun, S You, X Du, A Spaulding, ZG Liu, EJ Chaney, DR Spillman Jr, …
Quantitative Imaging in Medicine and Surgery 10 (11), 2177-2190
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35 | 2020 |
| Simultaneous two-photon activation and imaging of neural activity based on spectral–temporal modulation of supercontinuum light
YZ Liu, C Renteria, CD Courtney, B Ibrahim, S You, EJ Chaney, …
Neurophotonics 7 (4), 045007-045007
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18 | 2020 |
| Imaging heterogeneity of NAD (P) H in individual extracellular vesicles using fluorescence lifetime imaging microscopy (FLIM)
JE Sorrells, EM Martin, P Mukherjee, E Aksamitiene, S You, A Alex, …
Microscopy Histopathology and Analytics, MW1A. 3
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2020 | |
| Characterizing treatment response of pancreatic tumor patient-derived xenografts in mice by Simultaneous Label-Free Autofluorescence Multi-Harmonic (SLAM) microscopy
J Park, E Chaney, S You, AM Abdelrahman, JL Leiting, JA Yonkus, …
Clinical and Translational Biophotonics, TM2B. 4
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2020 | |
| Label-free multi-modal multiphoton imaging for real-time point-of-procedure assessment of core-needle and fine-needle biopsy specimens (Conference Presentation)
L Yang, Y Sun, DR Spillman Jr, S You, SA Boppart
Optical Biopsy XVIII: Toward Real-Time Spectroscopic Imaging and Diagnosis …
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2020 | |
| REAL-TIME HISTOLOGY-LIKE VIDEO OF BLOOD FLOW CONCATENATED WITH THE ORIGINAL LABEL-FREE SLAM VIDEO COLLECTED FROM IN VIVO RAT MAMMARY TISSUE
YI SUN, S YOU, X DU, ZG LIU, EJ CHANEY, J SPILLMAN, …
AME SURGICAL VIDEO DATABASE Учредители: AME Publishing Company 7, 220
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2020 | |
| ROTATIONAL VIEW OF THE HISTOLOGY-LIKE 3D TISSUE STRUCTURE RECONSTRUCTED FROM FIGURE 6
YI SUN, S YOU, X DU, A SPAULDING, ZG LIU, EJ CHANEY, J SPILLMAN, …
AME SURGICAL VIDEO DATABASE Учредители: AME Publishing Company 7, 222
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2020 | |
| ANIMATED DEPTH-RESOLVED 3D IMAGE STACK OF RAT MAMMARY TUMOR MICROENVIRONMENT RENDERED FROM FIGURE 6
YI SUN, S YOU, X DU, A SPAULDING, ZG LIU, EJ CHANEY, J SPILLMAN, …
AME SURGICAL VIDEO DATABASE Учредители: AME Publishing Company 7, 221
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2020 | |
| Real-time intraoperative diagnosis by deep neural network driven multiphoton virtual histology
S You, Y Sun, L Yang, J Park, H Tu, M Marjanovic, S Sinha, SA Boppart
NPJ precision oncology 3 (1), 33
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52 | 2019 |
| Multiphoton microscopy for stain-free slide-free histopathology
S You
University of Illinois at Urbana-Champaign
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2019 | |
| Label-free visualization and characterization of extracellular vesicles in breast cancer
S You, R Barkalifa, EJ Chaney, H Tu, J Park, JE Sorrells, Y Sun, YZ Liu, …
Proceedings of the National Academy of Sciences 116 (48), 24012-24018
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96 | 2019 |
| Molecular imaging biomarkers
SA Boppart, H Tu, S You, Y Liu
|
2019 | |
| Molecular imaging biomarkers
SA Boppart, H Tu, S You, Y Liu
US Patent 10,445,880
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5 | 2019 |
| Simultaneous label-free autofluorescence-multiharmonic microscopy and beyond
SA Boppart, S You, L Li, J Chen, H Tu
APL photonics 4 (10)
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39 | 2019 |
| Detection of weak near-infrared optical imaging signals under ambient light by optical parametric amplification
Y Sun, H Tu, S You, C Zhang, YZ Liu, SA Boppart
Optics letters 44 (17), 4391-4394
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27 | 2019 |
| Label-free optical imaging and characterization of cancer-associated urinary extracellular vesicles: Implications for biomarker discovery
R Barkalifa, S You, H Tu, A Masyr, R Kamerer, M Marjanovic, J Park, …
Cancer Research 79 (13_Supplement), 1936-1936
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2019 | |
| Label-free molecular profiling for identification of biomarkers in carcinogenesis using multimodal multiphoton imaging
Y Liu, H Tu, S You, EJ Chaney, M Marjanovic, SA Boppart
Quantitative Imaging in Medicine and Surgery 9 (5), 742
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20 | 2019 |
| Intraoperative visualization of the tumor microenvironment and quantification of extracellular vesicles by label-free nonlinear imaging
Y Sun, S You, H Tu, DR Spillman Jr, EJ Chaney, M Marjanovic, J Li, …
Science Advances 4 (12), eaau5603
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106 | 2018 |
| Slide-free virtual histochemistry (Part I): development via nonlinear optics
S You, Y Sun, EJ Chaney, Y Zhao, J Chen, SA Boppart, H Tu
Biomedical Optics Express 9 (11), 5240-5252
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44 | 2018 |
| Slide-free virtual histochemistry (Part II): detection of field cancerization
S You, Y Sun, EJ Chaney, Y Zhao, J Chen, SA Boppart, H Tu
Biomedical Optics Express 9 (11), 5253-5268
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36 | 2018 |
| Optical parametric amplification of gated confocal reflectance microscopy signals in scattering media
Y Sun, H Tu, S You, S Boppart
Laser Science, JTu3A. 114
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2018 | |
| Label-free detection and identification of cancer-associated vesicles in human breast cancer
S You, Y Sun, H Tu, R Barkalifa, EJ Chaney, M Marjanovic, AM Higham, …
Cancer Research 78 (13_Supplement), 3044-3044
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2018 | |
| Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
S You, H Tu, EJ Chaney, Y Sun, Y Zhao, AJ Bower, YZ Liu, M Marjanovic, …
Nature communications 9 (1), 2125
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311 | 2018 |
| Intraoperative determination of tumor aggressiveness by real-time label-free nonlinear imaging and characterization of tumor-associated extracellular vesicles (Conference …
Y Sun, S You, H Tu, DR Spillman Jr, M Marjanovic, EJ Chaney, GZ Liu, …
Molecular-Guided Surgery: Molecules, Devices, and Applications IV 10478, 1047805
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2018 | |
| Intracellular imaging of docosanol in living cells by coherent anti-Stokes Raman scattering microscopy
S You, Y Liu, Z Arp, Y Zhao, EJ Chaney, M Marjanovic, SA Boppart
Journal of biomedical optics 22 (7), 070502-070502
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15 | 2017 |
| Photonic crystal fiber-generated coherent supercontinuum for fast stain-free histopathology and intraoperative multiphoton imaging (Conference Presentation)
H Tu, S You, Y Sun, DR Spillman Jr, PS Ray, G Liu, SA Boppart
Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial …
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2017 | |
| Intra-operative label-free multimodal multiphoton imaging of breast cancer margins and microenvironment (Conference Presentation)
Y Sun, S You, H Tu, DR Spillman Jr, M Marjanovic, EJ Chaney, GZ Liu, …
Diagnosis and Treatment of Diseases in the Breast and Reproductive System …
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2017 | |
| Concurrence of extracellular vesicle enrichment and metabolic switch visualized label-free in the tumor microenvironment
H Tu, Y Liu, M Marjanovic, EJ Chaney, S You, Y Zhao, SA Boppart
Science advances 3 (1), e1600675
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55 | 2017 |
| Rapid diagnosis and differentiation of microbial pathogens in otitis media with a combined Raman spectroscopy and low-coherence interferometry probe: toward in vivo implementation
Y Zhao, GL Monroy, S You, RL Shelton, RM Nolan, H Tu, EJ Chaney, …
Journal of biomedical optics 21 (10), 107005-107005
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22 | 2016 |
| Raman spectroscopic analysis reveals abnormal fatty acid composition in tumor micro-and macroenvironments in human breast and rat mammary cancer
S You, H Tu, Y Zhao, Y Liu, EJ Chaney, M Marjanovic, SA Boppart
Scientific reports 6 (1), 32922
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56 | 2016 |
| Stain-free histopathology by programmable supercontinuum pulses
H Tu, Y Liu, D Turchinovich, M Marjanovic, JK Lyngsø, J Lægsgaard, …
Nature photonics 10 (8), 534-540
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276 | 2016 |
| Spectroscopic Raman analysis of tumor micro-And macroenvironments in human breast and rat mammary cancer
S You, H Tu, Y Zhao, Y Liu, EJ Chaney, M Marjanovic, SA Boppart
Cancer Imaging and Therapy, CTu4A. 5
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2016 | |
| Raman spectroscopic analysis of fatty acids in tumor micro-and macroenvironments in breast cancer
S You
University of Illinois at Urbana-Champaign
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1 | 2015 |
| Suppressing short-term polarization noise and related spectral decoherence in all-normal dispersion fiber supercontinuum generation
Y Liu, Y Zhao, J Lyngsø, S You, WL Wilson, H Tu, SA Boppart
Journal of lightwave technology 33 (9), 1814-1820
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69 | 2015 |
| Conference 9303D: Diagnosis and Treatment of Diseases in the Breast and Reproductive System
S You, Y Liu, H Tu, EJ Chaney, M Marjanovic, SA Boppart
The Moscone Center San Francisco, California, USA Conferences & Courses 7–12 …
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2015 | |
| Noninvasive vasculature detection using laser speckle imaging in avian embryos through intact egg in early incubation stage
L Yang, S You, L Zhang, T Yang, P Li, J Lu
Biomedical optics express 4 (1), 32-37
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34 | 2012 |
| Tag: Frank Cichos
G Volpe, C Wählby, L Tian, M Hecht, A Yakimovich, K Monakhova, …
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